Free Software for SQLite
Antares SQL
Antares SQL is an open source SQL client made to be simple. It's a modern, fast and productivity driven, and forever 100% free solution with a focus in UX.
Litestream
With Litestream you can stop building slow, complex, fragile software systems and use SQLite instead. Litestream continuously stream SQLite changes to S3-compatible storage. Allowing developers to build SQLite-powred application that can quickly recover to the point of failure if your server goes down. The Litestream command line also provides several subcommands to help you manage replication & recovery of your databases. This reference provides details about the options available and different modes of operation.
Objection.js
Objection.js is an ORM (Object Relational Mapper) built on top of knex for Node.js. Objection.js aims to stay out of your way and make it as easy as possible to use the full power of SQL and the underlying database engine while still making the common stuff easy and enjoyable. Even though ORM is the best commonly known acronym to describe objection, a more accurate description is to call it a relational query builder. With Objection.js you get all the benefits of an SQL query builder but also a powerful set of tools for working with relations.
Therapeutic Fc Characterization
Therapeutic antibody development and production are significant components of the biopharmaceutical sector and have had a significant positive impact on public health. To be clinically effective, therapeutic antibodies must perform two different types of functions: (i) target-specific binding via variable domains, and (ii) immune-mediated effector function via interaction of Fc (crystalllizable fragment) domains with cell receptors and complement proteins. By attaching to Fc-receptors (FcR) on immune cells or repairing complement, antibodies and antibody-based therapies have the potential to enhance immune function. The Fc region of the mAb must be described for IND and BLA submissions in accordance with the ICH Q6B and EMA mAb criteria. Therapeutic Fc characterisation was developed to promote the development of biobetter or biosimilar treatments after focusing on the development of antibody therapeutics for many years. In particular, we offer services for Fc engineering to control antibody function as well as cell-based functional tests for assessing antibody effector activities.