Piskel

vs

Adobe Photoshop

Pyxel Edit is a pixel art drawing application designed for working with pixel art and tiles. With Pyxel Edit you can game levels from tiles of sptrites. Create, import and export tilesets and level data directly from the editor and use them in your game. The tiles can flipped, rotated and mirrored allowing designers to quickly mock and create game levels and necessary data.

Pixie Engine Editor is a free, web-based graphics editor specifically designed for pixel art and animation.

Aseprite is a pixel art software for macOS, Linux and Windows with which you can create animated sprites and graphics. Aseprite is much used tool in the pixel art and indie game development scene where the tool allow designers to gets down to the nitty-gritty and create amazing pixel sprites and animations.

GIMP is a free and open-source raster graphics editor developed by the Free Software Foundation (GNU). The software is a perfect fit for anyone looking for a free and open alternative to Adobe Photoshop. GIMP can be used for photo retouching, image editing and composition. The software is commonly know within the Linux community but is available under the GPLv3+ licenses for macOS and Windows as well.

Pixelmator Pro is an image editor designed for professionals, yet accessible to everyone. The software developed specifically for Apple devices by Lithuanian brothers Saulius and Aidas Dailide. Pixelmator Pro is used for retouching photos, creating graphic designs, painting, drawing vector graphics, and adding stunning effects to your design projects.

Affinity Photo is a commercial full-featured raster graphics editor developed by Serif. The software is released as trio of software including Affinity Designer and Affinity Publisher. With Affinity Photo users can work natively with the full 32-bit image while using extensive tone mapping, which yields professionals results. Affinity Photo is available for iOS, macOS and Windows.