macrophage marker development

Classically (M1) and alternatively activated (M2) macrophages exhibit distinct functions. In vivo, there is a spectrum of macrophage phenotypes exists, and in vitro, there is low or non-selective M2 marker protein expression. Therefore, by leveraging the wealth of knowledge that we have on macrophage marker development, Creative Biolabs performs the most comprehensive analysis of the transcriptional signature of M1 and M2 macrophages in humans and mice. Our strategy can identify M1-exclusive or M2-exclusive markers, which can be used to distinguish between M1 and M2 macrophages. Our skilled scientists provide efficiencies with shorter timelines to accelerate our clients' M1/M2 macrophage marker development projects.