Polysaccharide coated liposome development

Polysaccharide coated liposomes are considered to be a physically and chemically stable system that can resist biochemical and physicochemical stresses in biological fluids. Some characteristics of them make their application in drug delivery rationalized: When plasma/serum or its components are present, the permeability of water-soluble encapsulated materials is reduced; Improve the stability against enzymatic attack and protect phospholipids from lipase and lipoxygenase; Mechanical and biochemical stability of biological stimuli, such as pH, osmotic pressure, ionic strength, temperature and dynamic challenges of biological fluids.