Koa

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FastAPI

AdonisJS is a Node.js web framework designed for building micro-services with JavaScript and Typescript. The framework provides an elegant syntax and and the tools that gives developers the confidence to build structured projects at scale. AdonisJS also includes its own ORM called Lucid, which is an implementation of Active Record, written in JavaScript. The framework will make anyone coming from Laravel or Ruby on Rails to feel right at home in the JavaScript eco-system.

Build powerful, scalable applications, with minimal overhead and full out-of-the-box functionality with Hapi. It's a free and open-source JavaScript framework for Node.js that is developed for enterprise-grade applications. Companies like Walmart, Brave and Condé Nast build web-services with Hapi and rely on it at scale.

Express.js is a free and open-source web application framework for Node.js, released as free and open-source software under the MIT License. Express is designed for building fast web applications and APIs. In the Node.js community the Express framework is seen as the defacto standard when it comes to building such applications. The philosophy of the framework is to provide a small and robust toolset for building HTTP servers with JavaScript and Node.js. Express does not force you to use any specific database, ORM or templating language, as it leaves that up to you as a developer, to maximize freedom and choice. Express.js is used by companies and hobby developers alike to build single page JavaScript applications, websites, hybrids and public HTTP APIs.

Flask is a micro framework framework written in Python that can be used to build APIs, web services and web applications. Flask is designed from the bottom up to be extremely minimal and easy to use, where your whole application can fit into one single Python file. The framework includes no database abstraction layer, form validation, or any other components, by design. However pre-existing third-party libraries provide common functionality needed to build production ready applications and services.

Bottle is a fast, simple and lightweight WSGI micro web-framework for Python. The framework can be used to create lean web applications with Python 2.7 and 3.x. Bottle is distributed as a single file module with no additional dependencies which makes it really easy to get started and later in the development-stage to manage.

Django is a high-level Python web development framework used for building web application at scale with speed. The framework adhere to a clean and pragmatic design that lets developers develop rapidly. Django ships as a "batteries included" framework and contains many of the features needed for most web applications such as an admin panel, an ORM and templating language. It takes much of the hassle out of web development and lets developers focus on writing their application instead of focusing on authentication, authorization and security.